７７－１ Proteo Inspection
○ By this examination, it is possible to risk judgment of cancers including pancreatic cancer from early stage by blood test. [1]
・With biochip using novel substance Silver Peroxide Meso Crystals: Proteo®, it is possible to determine the presence or absence of cancer, the type of cancer, and the degree of progress from stage 0 with a single drop of blood.
・Peroxide Meso Crystals, biochip Proteo® directly and quickly detects a tiny amount of cancer-related substances Nucleosomes existing in the blood, and makes it possible to distinguish the cancer in stage 0 and judge its progress.
※Nucleosomes：A nucleosome is a basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around eight histone protein cores.
・It was developed in collaboration with Showa University Hospital and Mytech Corporation.
※ Subject: Solid cancer such as pancreatic cancer, lung cancer, breast cancer, stomach cancer, liver cancer, colon cancer, tongue cancer, thyroid cancer, kidney cancer, prostate cancer, uterine cancer, ovarian cancer
※Proteo Inspection Image [3]
○NEWS
・20170301 Japan Society of Clinical Study for Frontier-Medicine（JSCSF）started clinical research..[2]
※List of laboratories
⇒MYTECH HOME
※ Inspection cost: about 500＄
７７－２ MicroRNA Inspection [4]
• Cancer cells secrete specific microRNAs.
• Evaluated 13 types of cancer in 4 grades.
• Cost: About 200＄
• Task: Even if it is not breast cancer, 20% is judged as cancer. It should be less than 5%.
• National Cancer Research Center (Tokyo) started clinical research in August 2017
• Project schedule: 2020 ~
【References】
1.”Silver Nanoscale Hexagonal Column Chips for Detecting Cell-free DNA and Circulating Nucleosomes in Cancer Patients” at nature.com 20150521
2. 一般社団法人 日本先進医療臨床研究会”「プロテオ検査」の実施と臨床研究開始のお知らせ”
3. “PROTEO(R)”at Mytech
4.THA YOMIURI SHIMBUN 20170812（Toll）
https://yomidr.yomiuri.co.jp/article/20170814-OYTET50027/
【Change log】
20170307 Start
20170804 Addition of Subject
20170818 Addition of MicroRNA Inspection
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